To compare I'm going to take a look at the two most gender biased websites on the 'net: Pinterest and Reddit. Both sites are bastions of gender so let's take a look at what each has that appeals to the appropriate sex.
The most noticeable difference between the two sites is how they organize information. Pinterest has a heavily designed homepage which show large, appealing pictures with minimal explanation text. All actions a user can take are made clear via large friendly buttons.
On the other hand is Reddit, whose design is focused on logically and simply displaying as much diverse information as uniformly as possible. New users describe the design as confusing and intimidating, and older users see understanding the site as a rite of passage. Possible actions a user can take are all visible though often not clearly explained.
I'd say women's networks are more visual and simple, where mens networks are more customizable but complex.